BDBM50627889 CHEMBL5440549

SMILES N[C@@H](CCCNC(N)=N)C(=O)NCCCCCCNC(=O)c1ccc(NC(=O)c2ccc(CN(C3CC3)C(=O)c3ccc4NC(=O)COc4c3)cc2)cc1

InChI Key InChIKey=XRTKGOLGVZDDJM-UHFFFAOYSA-N

Data  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50627889   

TargetHistone-lysine N-methyltransferase NSD2(Human)
University of Texas Medical Branch (UTMB)

Curated by ChEMBL
LigandPNGBDBM50627889(CHEMBL5440549)
Affinity DataKd:  14nMAssay Description:Binding affinity to NSD2 PWWP1 domain (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
University of Texas Medical Branch (UTMB)

Curated by ChEMBL
LigandPNGBDBM50627889(CHEMBL5440549)
Affinity DataEC50:  1.20E+3nMAssay Description:Induction of degradation of NSD2 in human U2OS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed