BDBM50627875 CHEMBL5401805

SMILES c1cc(sc1)CN(C2CC2)C(=O)c3ccc4c(c3)OCC(=O)N4

InChI Key InChIKey=XPHOPAPMJBSLFN-UHFFFAOYSA-N

Data  2 Kd

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50627875   

TargetHistone-lysine N-methyltransferase NSD2(Human)
University of Texas Medical Branch (UTMB)

Curated by ChEMBL
LigandPNGBDBM50627875(CHEMBL5401805)
Affinity DataKd:  3.40E+3nMAssay Description:Binding affinity to NSD2 PWWP1 domain (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase NSD2(Human)
University of Texas Medical Branch (UTMB)

Curated by ChEMBL
LigandPNGBDBM50627875(CHEMBL5401805)
Affinity DataKd:  349nMAssay Description:Binding affinity to human biotinylated NSD2 (208 to 368 residues) expressed in Escherichia coli BL21(DE3) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)