BDBM50627211 CHEMBL5430597

SMILES CCc1c(F)ccc2cc(O)cc(-c3ncc4c(cc(nc4c3F)C#C[C@@]34CCCN3C[C@H](F)C4)N3CC4CCC(C3)N4)c12

InChI Key InChIKey=XEANRMLMUAZOBH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50627211   

TargetGTPase KRas(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50627211(CHEMBL5430597)
Affinity DataIC50: 305nMAssay Description:Inhibition of KRAS G12D mutant in human PANC-1 cells assessed as reduction in phosphorylation of ERK 1/2 level incubated for 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed