BDBM50627205 CHEMBL5406644

SMILES Oc1cc(N2CCc3c(C2)nc(OCC24CCCN2CCC4)nc3N2CC3CCC(C2)N3)c2c(Cl)cccc2c1

InChI Key InChIKey=IWIITUGJHSVZBL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50627205   

TargetGTPase KRas(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50627205(CHEMBL5406644)
Affinity DataIC50: 15nMAssay Description:Inhibition of KRAS G12D mutant in human PANC-1 cells assessed as reduction in phosphorylation of ERK 1/2 level incubated for 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed