BDBM50627201 CHEMBL5402764

SMILES Cn1nc2CSCc3cnn(C)c3-c3c(Cl)ccc4c(CCCOc5cc(CCc1c2)cc1cc(F)ccc51)c(C(O)=O)n(CCN1CCOCC1)c34

InChI Key InChIKey=DGDUGLCJDSJQMR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50627201   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50627201(CHEMBL5402764)
Affinity DataKi:  0.0200nMAssay Description:Displacement of Cy5-labeled BIM BH3 peptide (H3N-(C/Cy5Mal)-WIAQELRRIGDEFN-OH) from MCL-1 (unknown origin) assessed as inhibition constant incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed