BDBM50627102 CHEMBL5408740

SMILES [H][C@@]12CCN(c3nc4nc(ccc4o3)-c3c(C)cc(Cl)cc3O)[C@]1([H])CN(C)CC2

InChI Key InChIKey=CTFYXPXBECKPTA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50627102   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50627102(CHEMBL5408740)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as reduction in pyroptosis preincubated for 3 hrs followed by nigericin addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed