BDBM50627079 CHEMBL5407794

SMILES COc1cc(O)c(Cl)cc1\C=C\C(=O)c1ccc(O)c(c1)[N+]([O-])=O

InChI Key InChIKey=WSTLIYMZLRFRFK-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50627079   

TargetDipeptidyl peptidase 4(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50627079(CHEMBL5407794)
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of DPP4 in human plasma using GP-BAN as fluorescent substrate preincubated for 5 mins followed by substrate addition and measured for 20 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50627079(CHEMBL5407794)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human FAP using Z-GP-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 20 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetProthrombin(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50627079(CHEMBL5407794)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant thrombin in human plasma using Z-Gly-Gly-Aly AMC as substrate preincubated for 3 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 9(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50627079(CHEMBL5407794)
Affinity DataIC50: 8.63E+4nMAssay Description:Inhibition of recombinant human DPP9 using Z-GP-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 20 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50627079(CHEMBL5407794)
Affinity DataIC50: 6.21E+4nMAssay Description:Inhibition of recombinant human PREP using Z-GP-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 20 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50627079(CHEMBL5407794)
Affinity DataIC50: 4.87E+3nMAssay Description:Inhibition of recombinant human DPP4 using GP-BAN as substrate preincubated for 5 mins followed by substrate addition and measured after 20 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50627079(CHEMBL5407794)
Affinity DataKi:  960nMAssay Description:Mixed type inhibition of DPP4 (unknown origin) using varying concentrations of GP-BAN as substrate assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed