BDBM50627009 CHEMBL5425308

SMILES CCCSc1nc(Oc2c(OC)cc(CN[C@@H]3C[C@H]3c3ccc(F)c(F)c3)cc2OC)c2nnn(Cc3cccc(Cl)c3)c2n1

InChI Key InChIKey=PRGXXJVBLCZSOL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50627009   

TargetLysine-specific histone demethylase 1A(Human)
Henan University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50627009(CHEMBL5425308)
Affinity DataIC50: 52nMAssay Description:Inhibition of full length LSD1 (unknown origin) using H3K4me2 peptide as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Henan University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50627009(CHEMBL5425308)
Affinity DataKi:  34nMAssay Description:Binding affinity to full length LSD1 (unknown origin) assessed as inhibition constant using H3K4me2 peptide as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed