BDBM50626658 CHEMBL5409736

SMILES Cc1nc2NC(=O)\C(=C/c3ccc4ccccc4n3)c2c(C)c1O

InChI Key InChIKey=CSKXBCHNPARCGH-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50626658   

TargetVascular endothelial growth factor receptor 2(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626658(CHEMBL5409736)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human VEGFR2 using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626658(CHEMBL5409736)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human PDGFRbeta using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626658(CHEMBL5409736)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human c-Kit using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626658(CHEMBL5409736)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human FGFR1 using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626658(CHEMBL5409736)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human FLT3 using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626658(CHEMBL5409736)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human CSF1R using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626658(CHEMBL5409736)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of human EGFR using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed