BDBM50626608 CHEMBL5429737

SMILES C[C@H](CO)n1ccc2c(NC(=O)CC34CC5CC(CC(C5)C3)C4)cccc2c1=O

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50626608   

TargetP2X purinoceptor 7(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50626608(CHEMBL5429737)
Affinity DataIC50: 1nMAssay Description:Inhibition of P2X7 (unknown origin) assessed as reduction in IL-1 beta releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50626608(CHEMBL5429737)
Affinity DataIC50: 520nMAssay Description:Inhibition of P2X7 in human THP-1cells assessed as reduction in YO-PRO-1 iodide dye uptake measured after 24 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed