BDBM50626577 CHEMBL5396078

SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC)-c3nnc(CNCC4CC4)o3)ncc2N(C)C1=O

InChI Key InChIKey=SMGYMGPXTAUBHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50626577   

TargetSerine/threonine-protein kinase PLK1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50626577(CHEMBL5396078)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of PLK1 (unknown origin) preincubated for 10 mins followed by substrate addition measured after 60 mins in presence of ATP by ADP-Glo assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details Article
PubMed