BDBM50626459 CHEMBL5398650

SMILES CC1=NN(C(=O)\C1=C\c1ccc(cc1)C(O)=O)c1nc(cs1)-c1ccc(Cl)cc1

InChI Key InChIKey=BASVBEFRHZKYIH-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50626459   

TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 210nMAssay Description:Inhibition of human SIRT5 by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 250nMAssay Description:Inhibition of human SIRT5 in presence of 800 uM NAD+ by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 240nMAssay Description:Inhibition of human SIRT5 in presence of 400 uM NAD+ by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 210nMAssay Description:Inhibition of human SIRT5 in presence of 200 uM NAD+ by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 260nMAssay Description:Inhibition of human SIRT5 in presence of 100 uM NAD+ by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 260nMAssay Description:Inhibition of human SIRT5 in presence of 50 uM NAD+ by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 720nMAssay Description:Inhibition of human SIRT5 in presence of 270 uM Ac-K(Suc)-AMC by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 580nMAssay Description:Inhibition of human SIRT5 in presence of 90 uM Ac-K(Suc)-AMC by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 340nMAssay Description:Inhibition of human SIRT5 in presence of 30 uM Ac-K(Suc)-AMC by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 210nMAssay Description:Inhibition of human SIRT5 in presence of 10 uM Ac-K(Suc)-AMC by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed