BDBM50626351 CHEMBL5436505

SMILES OCCN1CCN(Cc2cn(nn2)-c2cccc(NC(=O)c3cc(F)cc(F)c3)c2)CC1

InChI Key InChIKey=HVJJVFGMNLSTHA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50626351   

TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50626351(CHEMBL5436505)
Affinity DataIC50: 18nMAssay Description:Inhibition of TRKA (unknown origin) incubated for 1 hr by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50626351(CHEMBL5436505)
Affinity DataIC50: 16nMAssay Description:Inhibition of TRKB (unknown origin) incubated for 1 hr by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50626351(CHEMBL5436505)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of TRKC (unknown origin) incubated for 1 hr by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed