BDBM50626246 CHEMBL5430177

SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1cc(Oc2ccc(cc2)\N=N\c2ccc(Oc3cc(cc4c(C)ncnc34)-c3cnc(OC)c(NS(=O)(=O)c4ccc(F)cc4F)c3)cc2)c2ncnc(C)c2c1

InChI Key InChIKey=ZXOIHJSAGGLCHH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50626246   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Peking Union Medical College

Curated by ChEMBL

LigandBDBM50626246(CHEMBL5430177)Copy SMILESCopy InChI

Affinity DataIC50: 18nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate incubated for 1 hr in presence of ATP under dark condition by ADP-Glo luminescent as...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/18/2024
Entry Details
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