BDBM50626170 CHEMBL5403157

SMILES [2H]C([2H])([2H])CC(=O)c1cnc(NC(=O)C2CC2)cc1Nc1cccc2-c3nn(C)cc3C([2H])([2H])N(C)c12

InChI Key InChIKey=DPZUPMJWWNZNAM-JQKGTWBISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50626170   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50626170(CHEMBL5403157)
Affinity DataIC50: 30nMAssay Description:Inhibition of TYK2 in HEK-Blue IL-23 cells pretreated for 60 mins followed by IL-23 stimulation for 22 to 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50626170(CHEMBL5403157)
Affinity DataIC50: 30nMAssay Description:Inhibition of TYK2 in HEK-Blue alpha/beta cells pretreated for 60 mins followed by IFN-alpha stimulation for 16 to 18 hrs by Quanti-Blue based SEAP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed