BDBM50626136 CHEMBL5434708

SMILES CCCCNc1nc(N)nc2cnn(Cc3ccccc3)c12

InChI Key InChIKey=SKMQCQNNINVDGF-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50626136   

TargetToll-like receptor 7(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626136BDBM50626136(CHEMBL5434708)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human TLR7 by reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626136BDBM50626136(CHEMBL5434708)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at TLR7 in HEK-Blue hTLR7 cells coexpressing SEAP reporter transgene assessed as SEAP level incubated for 18 hrs by SEAP reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetToll-like receptor 8(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626136BDBM50626136(CHEMBL5434708)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at TLR8 in HEK-Blue hTLR8 cells coexpressing SEAP reporter transgene assessed as SEAP level incubated for 18 hrs by SEAP reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed