BDBM50626134 CHEMBL5413224

SMILES CCCCNc1nc(N)nc2cnn(Cc3ccc(CNC4CCC4)cc3OC)c12

InChI Key InChIKey=YHLMNHFXQQXBQC-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50626134   

TargetToll-like receptor 8(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50626134(CHEMBL5413224)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at human TLR8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50626134(CHEMBL5413224)
Affinity DataEC50:  58nMAssay Description:Agonist activity at human TLR7 by reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetToll-like receptor 7(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50626134(CHEMBL5413224)
Affinity DataEC50:  121nMAssay Description:Agonist activity at mouse TLR7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50626134(CHEMBL5413224)
Affinity DataEC50:  58nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells harboring SEAP reporter transgene incubated for 18 hrs by quanti-blue reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetToll-like receptor 7(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50626134(CHEMBL5413224)
Affinity DataEC50:  121nMAssay Description:Agonist activity at mouse TLR7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed