BDBM50626126 CHEMBL5435487

SMILES CCCCNc1nc(N)nc2cnn(Cc3ccc(CN4CC5(CNC5)C4)cc3OC)c12

InChI Key InChIKey=QPRGDWJZBWCKMV-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50626126   

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50626126(CHEMBL5435487)
Affinity DataEC50:  293nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells incubated for 18 hrs by QUANTI-Blue reagent based SEAP reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetToll-like receptor 7(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50626126(CHEMBL5435487)
Affinity DataEC50:  1.76E+3nMAssay Description:Agonist activity at mouse TLR7 by SEAP reporter gene based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed