BDBM50625905 CHEMBL5396984::US20250059185, Example 69

SMILES COCCOc1cc(Cl)cc(c1)-c1c2CCN([C@@H](C)c2nn1C)C(=O)c1cccc(OC)c1Cl

InChI Key InChIKey=FWFIMVBFKQUPFQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50625905   

TargetMonoglyceride lipase(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50625905(CHEMBL5396984 | US20250059185, Example 69)
Affinity DataIC50: 3nMAssay Description:Inhibition of MAGL (unknown origin) using 2-arachidonoylglycerol as substrate preincubated with compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMonoglyceride lipase(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50625905(CHEMBL5396984 | US20250059185, Example 69)
Affinity DataIC50: 3nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent