BDBM50625843 CHEMBL5407144

SMILES CCc1nnc(NC(=S)NS(=O)(=O)c2ccc(C)cc2)s1

InChI Key InChIKey=IYAXZWPOUHIREN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50625843   

TargetDNA gyrase subunit B(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625843(CHEMBL5407144)
Affinity DataIC50: 3.17E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by microplate ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625843(CHEMBL5407144)
Affinity DataIC50: 7.81E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by mi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625843(CHEMBL5407144)
Affinity DataIC50: 470nMAssay Description:Inhibition of Staphylococcus aureus dihydrofolate reductase using dihydrofolate as substrate in presence of NADPH by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed