BDBM50625807 CHEMBL5400539

SMILES Fc1ccc(Nc2ncnc3cc(O[C@@H]4CCOC4)c(NC(=O)N\N=C\c4cnc(nc4)N4CCCC4)cc23)cc1Cl

InChI Key InChIKey=DIMLJOPEJOMHIT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50625807   

TargetEpidermal growth factor receptor(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50625807(CHEMBL5400539)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50625807(CHEMBL5400539)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed