BDBM50625701 CHEMBL5406774

SMILES COc1ccc(cc1)C(=O)NCCc1cn(Cc2cnc(C)nc2N)nn1

InChI Key InChIKey=KOFFFCYDNFWYBZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50625701   

LigandPNGBDBM50625701(CHEMBL5406774)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of porcine PDHc E1-subunit incubated for 30 mins followed by pyruvate addition in presence of thiamine pyrophosphate by microplate reader ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
LigandPNGBDBM50625701(CHEMBL5406774)
Affinity DataKi:  175nMAssay Description:Binding affinity to porcine PDHc E1-subunit assessed as inhibition constant incubated for 30 mins followed by pyruvate addition by microplate reader ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed