BDBM50625619 CHEMBL4752253

SMILES CN(C)C(=O)c1ccc(cc1O)-c1cc(no1)C(=O)N[C@@H]1CCc2ccccc12

InChI Key InChIKey=IXWUILRSNIQHDM-UHFFFAOYSA-N

Data  5 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50625619   

TargetProtein ENL(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50625619(CHEMBL4752253)
Affinity DataIC50: 140nMAssay Description:Inhibition of MLLT1 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetProtein AF-9(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50625619(CHEMBL4752253)
Affinity DataIC50: 160nMAssay Description:Inhibition of MLLT3 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50625619(CHEMBL4752253)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of YEATS2 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50625619(CHEMBL4752253)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of YEATS4 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetProtein ENL(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50625619(CHEMBL4752253)
Affinity DataKd:  110nMAssay Description:Binding affinity to MLLT1 YD domain (unknown origin) assessed as dissociation constant by biolayer interferometry assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetProtein AF-9(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50625619(CHEMBL4752253)
Affinity DataKd:  110nMAssay Description:Binding affinity to MLLT3 YD domain (unknown origin) assessed as dissociation constant by biolayer interferometry assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetProtein ENL(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50625619(CHEMBL4752253)
Affinity DataKd:  82nMAssay Description:Binding affinity to MLLT1 YD domain (unknown origin) assessed as dissociation constant by isothermal calorimetry assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetProtein AF-9(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50625619(CHEMBL4752253)
Affinity DataKd:  76nMAssay Description:Binding affinity to MLLT3 YD domain (unknown origin) assessed as dissociation constant by isothermal calorimetry assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetProtein AF-9(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50625619(CHEMBL4752253)
Affinity DataIC50: 760nMAssay Description:Binding affinity to MLLT3 in human HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed