BDBM50625549 CHEMBL5410251

SMILES Cc1cc(=O)c(nn1-c1ccccc1)C(=O)NCc1c(F)cc(cc1F)-c1cccc(c1)S(F)(=O)=O

InChI Key InChIKey=KCMSIHHWMOTDFN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50625549   

TargetWD repeat-containing protein 5(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50625549(CHEMBL5410251)
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of N-terminal his-tagged WDR5 (1 to 334 residues) (unknown origin) measured after 10 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50625549(CHEMBL5410251)
Affinity DataIC50: 790nMAssay Description:Inhibition of N-terminal his-tagged WDR5 (1 to 334 residues) (unknown origin) measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50625549(CHEMBL5410251)
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal his-tagged WDR5 (1 to 334 residues) (unknown origin) measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50625549(CHEMBL5410251)
Affinity DataIC50: 170nMAssay Description:Inhibition of N-terminal his-tagged WDR5 (1 to 334 residues) (unknown origin) measured after 180 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50625549(CHEMBL5410251)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal his-tagged WDR5 (1 to 334 residues) (unknown origin) measured after 360 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed