BDBM50625500 CHEMBL5419352::US12122780, Compound 39

SMILES CC(C)(O)CN1CCC(COc2cnc(nc2)-c2cccc(Cn3c4nc5ccc(cc5n4ccc3=O)C#N)c2)CC1

InChI Key InChIKey=NXYXHXOLWMFGJD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50625500   

TargetHepatocyte growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50625500(CHEMBL5419352 | US12122780, Compound 39)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of MET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50625500(CHEMBL5419352 | US12122780, Compound 39)
Affinity DataIC50: 5.51nMAssay Description:The kinase buffer in the kit was used to dilute the enzyme, substrate, ATP and inhibitor.The compound to be tested was diluted 5-fold to the eighth c...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/24/2025
Entry Details
Go to US Patent