BDBM50625491 CHEMBL5425306

SMILES COc1cc(C2CCN(CCCC#Cc3cccc4C(=O)N(Cc34)C3CCC(=O)NC3=O)CC2)c(C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1

InChI Key InChIKey=QJMDACHGDOVSAD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50625491   

TargetALK tyrosine kinase receptor(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50625491(CHEMBL5425306)
Affinity DataIC50: 542nMAssay Description:Inhibition of N-terminal flag-tagged NanoLuc fused ALK kinase domain (1072 to 1410 residues) (unknown origin) expressed in mouse BaF3 cells assessed ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed