BDBM50625428 CHEMBL5412271

SMILES CC(=O)N1CCN(Cc2cccc(Nc3ncc4ccn(CCCNC(=O)C5CCC5)c4n3)c2)CC1

InChI Key InChIKey=QVADRMQCYNOPPE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50625428   

TargetSerine/threonine-protein kinase TBK1(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50625428(CHEMBL5412271)
Affinity DataIC50: 22nMAssay Description:Inhibition of TBK1 (unknown origin) incubated for 1 hr in presence of ATP by FRET based Z'-Lyte assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50625428(CHEMBL5412271)
Affinity DataIC50: 566nMAssay Description:Inhibition of TBK1 in human THP1-Blue ISG cells by measuring SEAP gene expression incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50625428(CHEMBL5412271)
Affinity DataIC50: 22nMAssay Description:Inhibition of TBK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed