BDBM50625413 CHEMBL5415726

SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2ncc(-c3cn(CCN4CCN(C)CC4)nn3)n2n1

InChI Key InChIKey=MBDYLGBKRNAOKO-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50625413   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
East China Normal University

Curated by ChEMBL

LigandBDBM50625413(CHEMBL5415726)Copy SMILESCopy InChI

Affinity DataIC50: 0.170nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate incubated for 1 hr in presence of ATP by Kinase-Glo plus luminescent assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoSimilars

In Depth
Date in BDB:
12/18/2024
Entry Details
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