BDBM50625199 CHEMBL5399974

SMILES NS(=O)(=O)c1ccc2NC(C3CC=CC3c2c1)c1ccc(O)cc1Cl

InChI Key InChIKey=HLEVRSLETWDQBY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50625199   

TargetCarbonic anhydrase 9(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50625199(CHEMBL5399974)
Affinity DataKi:  56nMAssay Description:Binding affinity to human CA9 assessed as inhibition constant incubated for 6 hrs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50625199(CHEMBL5399974)
Affinity DataKi:  79nMAssay Description:Binding affinity to human CA12 assessed as inhibition constant incubated for 6 hrs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50625199(CHEMBL5399974)
Affinity DataKi:  539nMAssay Description:Binding affinity to human CA2 assessed as inhibition constant incubated for 6 hrs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50625199(CHEMBL5399974)
Affinity DataKi:  706nMAssay Description:Binding affinity to human CA1 assessed as inhibition constant incubated for 6 hrs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed