BDBM50624932 CHEMBL5427414

SMILES Oc1ccc(cc1O)-c1cccc2c1oc1ccccc21

InChI Key InChIKey=XIVRMGWIAVBXCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50624932   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50624932(CHEMBL5427414)
Affinity DataIC50: 76nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 5 to 10 mins w...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50624932(CHEMBL5427414)
Affinity DataIC50: 210nMAssay Description:Inhibition of 5-lipoxygenase in human PMNL cells using arachidonic acid as substrate preincubated with compound for 15 mins followed by A23187 and su...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed