BDBM50624923 CHEMBL5413658

SMILES Oc1ccc(cc1O)-c1cccc(Cl)c1

InChI Key InChIKey=VUJAOJNAJBGLGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50624923   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50624923(CHEMBL5413658)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 5 to 10 mins w...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50624923(CHEMBL5413658)
Affinity DataIC50: 210nMAssay Description:Inhibition of 5-lipoxygenase in human PMNL cells using arachidonic acid as substrate preincubated with compound for 15 mins followed by A23187 and su...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed