BDBM50624898 CHEMBL5416367

SMILES [H][C@]12C[C@@H](OP(=O)(OCCSC(=O)C(C)(C)C)OC[C@]3([H])C[C@@]([H])(OP(=O)(OCCSC(=O)C(C)(C)C)OC1)[C@@H](O3)n1cnc3ncnc(N)c13)[C@@H](O2)n1cnc2ncnc(N)c12

InChI Key InChIKey=FWMHECVBNXHNKA-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50624898   

TargetStimulator of interferon genes protein(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50624898(CHEMBL5416367)
Affinity DataEC50:  506nMAssay Description:Agonist activity at STING in human THP-1 reporter cells incubated for 24 hrs by QUANTI-Luc assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50624898(CHEMBL5416367)
Affinity DataEC50:  540nMAssay Description:Agonist activity at STING in human THP-1 reporter cells incubated for 4 hrs in presence of lipofectamine 2000 by QUANTI-Luc assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50624898(CHEMBL5416367)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at STING in PMA-treated human THP-1 reporter cells incubated for 30 mins in presence of digitonin by QUANTI-Luc assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed