BDBM50624895 CHEMBL5394677

SMILES Cn1ccc2c(Oc3ccc(NC(=O)Cc4ccc(c(F)c4)C(F)(F)F)cc3)ncnc12

InChI Key InChIKey=WIAYJYJAAXMOLH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50624895   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50624895(CHEMBL5394677)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of CSF1R (unknown origin) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ADP-Glo luminescence ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50624895(CHEMBL5394677)
Affinity DataIC50: 258nMAssay Description:Inhibition of PDGFR alpha (unknown origin) using TK as substrate incubated for 50 mins in presence of ATP by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50624895(CHEMBL5394677)
Affinity DataIC50: 197nMAssay Description:Inhibition of PDGFR beta (unknown origin) using TK as substrate incubated for 50 mins in presence of ATP by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50624895(CHEMBL5394677)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of FLT3 (unknown origin) using TK as substrate incubated for 50 mins in presence of ATP by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50624895(CHEMBL5394677)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of c-KIT (unknown origin) using TK as substrate incubated for 50 mins in presence of ATP by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed