BDBM50624814 CHEMBL5436647

SMILES COc1ccc(Cc2nnc(N3CCN(CC3)C(=S)Nc3ccc(Cl)cc3)c3ccccc23)cc1

InChI Key InChIKey=DJOPDQNHJUNVIQ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50624814   

TargetCyclin-dependent kinase 1(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50624814(CHEMBL5436647)
Affinity DataIC50: 50nMAssay Description:Inhibition of CDK1 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50624814(CHEMBL5436647)
Affinity DataIC50: 534nMAssay Description:Inhibition of CDK2 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 5(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50624814(CHEMBL5436647)
Affinity DataIC50: 716nMAssay Description:Inhibition of CDK5 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50624814(CHEMBL5436647)
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of AXL (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50624814(CHEMBL5436647)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of PTK2B (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50624814(CHEMBL5436647)
Affinity DataIC50: 4.35E+3nMAssay Description:Inhibition of FGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50624814(CHEMBL5436647)
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibition of JAK1 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50624814(CHEMBL5436647)
Affinity DataIC50: 7.44E+3nMAssay Description:Inhibition of IGF1R (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50624814(CHEMBL5436647)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of BRAF (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed