BDBM50624592 CHEMBL5404240

SMILES Cc1oc2ncn(CCCN3CCCC3)c(=O)c2c1C(=O)Nc1ccc(nc1)S(N)(=O)=O

InChI Key InChIKey=MDTLMYQHRYFTRJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50624592   

TargetDNA (cytosine-5)-methyltransferase 3-like(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624592(CHEMBL5404240)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of N-terminal His-tagged human DNMT3A (623 to 912 residues)/N-terminal GST-tagged human DNMT3L (160 to 387 residues) co-expressed in bacul...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624592(CHEMBL5404240)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of N-terminal GST-tagged full-length recombinant human DNMT1 assessed as DNA methylation using pdI-pdC DNA as substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624592(CHEMBL5404240)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of N-terminal His-tagged human DNMT3B (564 to 853 residues)/N-terminal GST-tagged human DNMT3L (160 to 387 residues) co-expressed in bacul...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624592(CHEMBL5404240)
Affinity DataIC50: 3.08E+5nMAssay Description:Inhibition of N-terminal GST-tagged human G9a expressed in baculovirus infected Sf9 cells using biotinylated histone H3 peptide as substrate preincub...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed