BDBM50624446 CHEMBL5428904

SMILES Nc1nonc1-c1nc2ccccc2n1CC(=O)Nc1cc(Cl)cc(c1)C(F)(F)F

InChI Key InChIKey=BTXUOKGSNSBXMC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50624446   

TargetCholinesterase(Horse)
Qingdao University

Curated by ChEMBL
LigandPNGBDBM50624446(CHEMBL5428904)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate incubated for 10 mins followed by substrate addition by DTNB-reagent ba...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Qingdao University

Curated by ChEMBL
LigandPNGBDBM50624446(CHEMBL5428904)
Affinity DataIC50: 113nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 10 mins followed by substrate addition by DTNB-reagent based Ell...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed