BDBM50624387 CHEMBL5419989

SMILES COc1ccc2c3CCN(Cc3oc2c1)[C@@H](Cc1ccccc1)C(=O)Nc1ccc(cc1)C(=O)NO

InChI Key InChIKey=KRBROHHVEWJNNM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50624387   

TargetHistone deacetylase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624387(CHEMBL5419989)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic Boc-Lys (aetyl)-AMC as substrate preincubated for 10 mins followed by substrate addition meas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624387(CHEMBL5419989)
Affinity DataIC50: 34nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624387(CHEMBL5419989)
Affinity DataIC50: 36nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624387(CHEMBL5419989)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624387(CHEMBL5419989)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624387(CHEMBL5419989)
Affinity DataIC50: 97nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624387(CHEMBL5419989)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed