BDBM50624358 CHEMBL5403275

SMILES [H][C@]12CS[C@@H](CCCCC(=O)NCCNC(=O)C3CCCCN3Cc3cc(Cl)c(OCc4cccc(c4C)-c4ccccc4)cc3OCc3cccc(c3)C#N)[C@@]1([H])NC(=O)N2

InChI Key InChIKey=YCHPIMKSTJPEFJ-UHFFFAOYSA-N

Data  1 IC50  3 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50624358   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50624358(CHEMBL5403275)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of GST-tagged PD-1 (unknown origin)/His-tagged PD-L1 (unknown origin) interaction by HTRF binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50624358(CHEMBL5403275)
Affinity DataKd:  44nMAssay Description:Binding affinity to human PD-L1 assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Mouse)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50624358(CHEMBL5403275)
Affinity DataKd:  218nMAssay Description:Binding affinity to mouse PD-L1 assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Mouse)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50624358(CHEMBL5403275)
Affinity DataKd:  438nMAssay Description:Binding affinity to mouse PD-L1 assessed as dissociation constant by MST analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50624358(CHEMBL5403275)
Affinity DataEC50:  920nMAssay Description:Inhibition of interaction of PD-1 (unknown origin) expressed in Jurkat T cells carrying luciferase reporter under the control of NFAT promoter/PD-L1 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed