BDBM50624233 CHEMBL5410802

SMILES ONC(=O)c1ccc(COc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)cc1

InChI Key InChIKey=CKHUIFFTCIFDOH-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50624233   

TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50624233(CHEMBL5410802)
Affinity DataIC50: 33nMAssay Description:Inhibition of N-terminal GST-tagged human full length recombinant HDAC6 (1 to 1215 residues) expressed in Sf9 cells using Boc-Lys(acetyI)-AMC as subs...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50624233(CHEMBL5410802)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of C-terminal FLAG-tagged human full length recombinant HDAC2 (1 to 488 residues) expressed in Sf9 cells using Boc-Lys(acetyI)-AMC as subs...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50624233(CHEMBL5410802)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of C-terminal His/FLAG-tagged human full length recombinant HDAC1 (1 to 482 residues) expressed in Sf9 cells using Boc-Lys(acetyI)-AMC as ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50624233(CHEMBL5410802)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of C-terminal His-tagged human HDAC3 (1 to 428 residues)/N-terminal GST-tagged human NCOR2 (395 to 489 residues) expressed in baculovirus-...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50624233(CHEMBL5410802)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged/C-terminal His-tagged human HDAC4 (627 to 1084 residues) expressed in baculovirus-infected Sf9 cells using Boc-Ly...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50624233(CHEMBL5410802)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human recombinant HDAC5 catalytic domain (656 to 1122 residues) expressed in baculovirus-infected Sf9 cells using...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50624233(CHEMBL5410802)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in baculovirus-infected Sf9 cells using Boc-Lys(trifluoroacety1)-AMC ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50624233(CHEMBL5410802)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of C-terminal His-tagged human full length recombinant HDAC8 (1 to 377 residues) expressed in Sf9 cells using Boc-Lys(trifluoroacety1)-AMC...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50624233(CHEMBL5410802)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human recombinant HDAC9 (604 to 1066 residues) expressed in baclovirus-infected Sf9 cells using Boc-Lys(trifluoro...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50624233(CHEMBL5410802)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of N-terminal FLAG-tagged human recombinant HDAC10 (2 to 631 residues) expressed in baculovirus-infected Sf9 cells using Acetyl-Arg-His-Ly...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50624233(CHEMBL5410802)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human full length recombinant HDAC11 (1 to 347 residues) expressed in Sf9 cells using acetyl-ETDKmyr-AMC as substrate preincubated with...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed