BDBM50623891 CHEMBL5431912

SMILES CC(c1ccc(F)cc1)n1cc(-c2cc(F)cc(F)c2)c(=O)[nH]c1=O

InChI Key InChIKey=LMEGWTNEOLAVKJ-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50623891   

TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50623891(CHEMBL5431912)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to wild type c-MET (unknown origin) assessed as dissociation constant measured for 120 sec by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50623891(CHEMBL5431912)
Affinity DataKd:  670nMAssay Description:Binding affinity to c-MET D1228V (unknown origin) assessed as dissociation constant measured for 120 sec by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed