BDBM50623811 CHEMBL5397552

SMILES CC(=O)N1CCc2c1ccc(c2Cl)Cl

InChI Key InChIKey=FSLARAPYXMNEFP-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50623811   

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50623811(CHEMBL5397552)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant Notum (81 to T451 residues) expressed in HEK293S cells using OPTS as substrate incubated for 40 mins by microplate re...More data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50623811(CHEMBL5397552)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of full length human recombinant Notum (81 to T451 residues) expressed in HEK293S cells using OPTS as substrate incubated for 40 mins by m...More data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)