BDBM50623661 CHEMBL5417606

SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3n(CCF)c4ccc(CC5CC5)cc4c3c2)cc1

InChI Key InChIKey=UQNCCNBBSDCYHR-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50623661   

TargetNuclear receptor ROR-gamma(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50623661(CHEMBL5417606)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human RORgammat LBD (265 to 507 residues) expressed in Escherichia coli BL21(DE3) cells incubated for 1 hr FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50623661(CHEMBL5417606)
Affinity DataEC50:  245nMAssay Description:Agonist activity at Gal4-fused human RORgammat LBD expressed in HEK293T cells assessed as luciferase activity incubated for 16 to 20 hrs by luciferas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed