BDBM50623601 CHEMBL5413511

SMILES CN([C@@H](Cc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(N)=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=DYEZJBVYRZIZOQ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50623601   

TargetGenome polyprotein(DENV-2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50623601(CHEMBL5413511)
Affinity DataIC50: 89nMAssay Description:Inhibition of DENV-2 NS2B-NS3 protease by biochemical enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetGenome polyprotein(WNV)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50623601(CHEMBL5413511)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease by biochemical enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50623601(CHEMBL5413511)
Affinity DataKi:  78nMAssay Description:Competitive inhibition of DENV-2 NS2B-NS3 protease assessed as inhibition constant by Cheng-Prusoff plot analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetGenome polyprotein(WNV)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50623601(CHEMBL5413511)
Affinity DataKi:  5.10E+3nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed