BDBM50623583 CHEMBL5421134

SMILES NC(=O)c1cccc(c1)-c1cnc2[nH]ccc2c1

InChI Key InChIKey=PQAJMNITAQGSCS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50623583   

TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50623583(CHEMBL5421134)
Affinity DataIC50: 52nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50623583(CHEMBL5421134)
Affinity DataIC50: 52nMAssay Description:Inhibition of CDK8/Cyclin C (unknown origin) preincubated for 10 mins followed by substrate addition measured for 60 to 120 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50623583(CHEMBL5421134)
Affinity DataIC50: 428nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 (unknown origin) preincubated for 10 mins followed by substrate addition measured for 60 to 120 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50623583(CHEMBL5421134)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CDK2/Cyclin E1 (unknown origin) preincubated for 10 mins followed by substrate addition measured for 60 to 120 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50623583(CHEMBL5421134)
Affinity DataIC50: 711nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin) preincubated for 10 mins followed by substrate addition measured for 60 to 120 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50623583(CHEMBL5421134)
Affinity DataIC50: 594nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin) preincubated for 10 mins followed by substrate addition measured for 60 to 120 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed