BDBM50623542 CHEMBL5440801

SMILES Cc1ccc(CCCN2CC3(C2)CN(C(=O)C3)c2ccccc2)cc1

InChI Key InChIKey=XRKKADYYRPDJSD-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50623542   

TargetSigma non-opioid intracellular receptor 1(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50623542(CHEMBL5440801)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at sigma1 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50623542(CHEMBL5440801)
Affinity DataIC50: 227nMAssay Description:Antagonist activity at sigma2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50623542(CHEMBL5440801)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane at 1 uM by liquid scintillation counting analysis relative to cont...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50623542(CHEMBL5440801)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane assessed as inhibition constant in presence of phenytoin by liquid...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed