BDBM50623515 CHEMBL5417235

SMILES Nc1ccccc1NC(=O)c1ccc(NC(=O)c2n[nH]cc2NC(=O)c2c(Cl)cccc2Cl)cc1

InChI Key InChIKey=DMHUURDTAWQEKB-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50623515   

TargetCyclin-dependent kinase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50623515(CHEMBL5417235)
Affinity DataIC50: 100nMAssay Description:Inhibition of CDK9 (unknown origin) preincubated for 20 mins followed by [gamma-33P]ATP addition measured after 120 mins in presence of ATP by Hot-Sp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50623515(CHEMBL5417235)
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human HDAC1 using HDAC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50623515(CHEMBL5417235)
Affinity DataIC50: 99nMAssay Description:Inhibition of recombinant human HDAC2 using HDAC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50623515(CHEMBL5417235)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human HDAC3 using HDAC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50623515(CHEMBL5417235)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human HDAC4 using HDAC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50623515(CHEMBL5417235)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human HDAC5 using HDAC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50623515(CHEMBL5417235)
Affinity DataIC50: 723nMAssay Description:Inhibition of recombinant human HDAC6 using HDAC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50623515(CHEMBL5417235)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human HDAC7 using HDAC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50623515(CHEMBL5417235)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of recombinant human HDAC8 using HDAC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50623515(CHEMBL5417235)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human HDAC9 using HDAC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50623515(CHEMBL5417235)
Affinity DataIC50: 98nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed