BDBM50623350 CHEMBL5427479

SMILES Clc1cc(Cl)cc(c1)C(=O)Nc1c2CSCc2nn1-c1ccc(Br)cc1

InChI Key InChIKey=YRJDZTVMROWBPE-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50623350   

TargetAutotaxin(Human)
Bioinnovation Institute

Curated by ChEMBL
LigandPNGBDBM50623350(CHEMBL5427479)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human ATX using LPC as substrate preincubated with compound for 15 mins followed by substrate addition measured after 30 mins by Amplex...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mouse)
Bioinnovation Institute

Curated by ChEMBL
LigandPNGBDBM50623350(CHEMBL5427479)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of mouse ATX using LPC as substrate preincubated with compound for 15 mins followed by substrate addition measured after 30 mins by Amplex...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAutotaxin(Human)
Bioinnovation Institute

Curated by ChEMBL
LigandPNGBDBM50623350(CHEMBL5427479)
Affinity DataKi:  6.26E+3nMAssay Description:Mixed type inhibition of human ATX assessed as inhibition constant using LPC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed