BDBM50623292 CHEMBL4176488

SMILES CC(C)Oc1cc(ccc1NC(=O)c1[nH]c(C)c(Cl)c1Cl)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI Key InChIKey=IOENDXXUMVWGKE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50623292   

TargetDNA topoisomerase 2-alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50623292(CHEMBL4176488)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human DNA topoisomerase 2 alpha assessed as relaxation of supercoiled plasmid pNO1 DNA incubated for 30 mins by fluorescence based anal...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed