BDBM50623244 CHEMBL5432018

SMILES Cc1[nH]c(C(=O)Nc2ccccc2OC2CCNCC2)c(Cl)c1Cl

InChI Key InChIKey=ZEDKFCQTUOZLNU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50623244   

TargetDNA topoisomerase 2-alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50623244(CHEMBL5432018)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 alpha assessed as relaxation of supercoiled plasmid pNO1 DNA incubated for 30 mins by fluorescence based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50623244(CHEMBL5432018)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 alpha assessed as ATP hydrolysis measured for 30 mins by absorbance based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed