BDBM50622924 CHEMBL5402846

SMILES Fc1ccc(CCNC(=O)c2ccc(CN(C(=O)N3CC[N+](CCCc4ccccc4)(Cc4ccc(Cl)c(Cl)c4)CC3)c3ccc(F)cc3)o2)cc1

InChI Key InChIKey=HMPPHVILQOCYRA-UHFFFAOYSA-O

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50622924   

TargetTrypanothione reductase(Leishmania infantum)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50622924(CHEMBL5402846)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of Leishmania infantum Trypanothione reductase expressed in Escherichia coli BL21 (DE3) using trypanothione as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTrypanothione reductase(Leishmania infantum)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50622924(CHEMBL5402846)
Affinity DataKi:  200nMAssay Description:Competitive inhibition of Leishmania infantum Trypanothione reductase expressed in Escherichia coli BL21 (DE3) using trypanothione as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed